Aug 23, 2025
3 min read
The same protein is to feed the brain's elderly and close the loss of reverse memory.
Researchers at UC San Francisco do not arise in a surprise crime in brain aging and the protein called FTL1.
In the excessive aging mice of this protein weaken memory and disrupt the nervous connection.But when scientists blocked FTL1, the brains in mice blind a youthful function and memory tests have improved dramatically.
Hopocomess forte
Aging takes heavy in the hypokampus, the part of the brain that conveys learning and memory.
Scientists of UC San Francisco have now identified a single protein, FTL1, which seems to play a major role in this age -related collapse.
The team found that in the study of how the sack and protein in Hippocampus at the time, only one and older animals: FTL 1.
Imitating old age in young brain
Old mice reduce the connection between higher level FTL1, hippocampus and weak memory performance.When researchers artificially increased FTL1 in young mice, their brains and actions quickly began to resemble older animals.
Cell cultural experiments in neurons for large amounts of FTL1 developed unusual.To grow complex, branched neuritis, they were just simple, disposable extensions.
Reversal of decreased memory below FTL1
If the Societals with hippocampus per disables by the old results were subject to.
"This is truly an upside of suffering," said Saul Wilda, Ph.D.
Metabolism, FTL1, hopefully for treatment
In larger rats, FTL1 reduced metabolism to hippocampus cells.
Flinka is good that works can make doctors who protect FTL1 from the brain.
"We believe that there are many opportunities that reduce the serious consequences," he said."
Directions: "The PORON-connected fort ftl1 in the brain of the most mental size, Alezan, Ju'du, Ju'son 2025, Anodan Ams.
Penulis: Penulis Ucsf lyyane Yaiku Remesal Laura, PhD, Juliana Sucharov-Kosta, Karishma J. B. PhD, PhD, PhD, PHD, brandon, ISHA H.jian, Jason C. Maynard, PHD, PHD, PHDL. Burlingame, PhD.
Support: This work was partly fulfilled by the Simons Foundation, Balbblom Foundation, Balclom Age Institute, and the National Ag081038, AG300).
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